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Baclofen / Diazepam Suppository
Compounded baclofen and diazepam suppositories are a prescription-only combination therapy used to manage pelvic floor dysfunction, muscle hypertonicity, and chronic pelvic pain. Baclofen acts as a GABA-B agonist to reduce involuntary muscle contractions, while diazepam offers additional muscle relaxation and anxiolytic effects. Administered rectally or vaginally, this dual-agent suppository delivers targeted relief directly to the pelvic region, commonly prescribed in urogynecology, physical therapy, and pain management settings. Our pharmacy compounds this formulation in custom strengths and bases tailored to provider-directed pelvic floor protocols.
Patients? Request More Information Prescribers? Request Prescribing AccessThis compounded suppository combines baclofen and diazepam — two complementary muscle relaxants — for stronger relief of tight, painful pelvic floor muscles. Together they ease the muscle spasm behind chronic pelvic pain, painful intercourse, vaginismus, and certain bladder and bowel symptoms more effectively than either alone. Delivered as a suppository, the medication concentrates on the pelvic floor while limiting the drowsiness of oral dosing, making it a valuable part of pelvic-floor therapy.
Prescribers and pelvic-health specialists choose this combination for patients whose pelvic muscle tension needs a stronger approach, often alongside physical therapy. We compound each suppository to the exact strengths your prescriber specifies, made to order in our pharmacy.
This suppository contains diazepam, a controlled substance, and is a compounded medication prepared to your prescription and used strictly under a prescriber's guidance. Your prescriber will set the dose, explain use, and monitor your progress. Every batch is pharmacist-compounded, quality-verified, and shipped nationwide. Prescription required.
Frequently asked questions
What does this suppository treat?
Tight, painful pelvic floor muscles behind chronic pelvic pain, painful intercourse, vaginismus, and some bladder or bowel symptoms.
Why combine two relaxants?
Baclofen and diazepam work through complementary mechanisms, so together they can relieve pelvic muscle spasm more effectively than either alone.
Is it used with physical therapy?
Often, yes — it's commonly part of a pelvic floor therapy plan coordinated by your prescriber.
Is it closely supervised?
Yes — because it contains diazepam, a controlled substance, it's used strictly under a prescriber's guidance with monitoring.
Do I need a prescription?
Yes. These suppositories are compounded to your prescriber's order and require a valid prescription. Our pharmacists prepare and verify every batch.
Compounded baclofen and diazepam suppositories are a prescription-only combination therapy used to manage pelvic floor dysfunction, muscle hypertonicity, and chronic pelvic pain. Baclofen acts as a GABA-B agonist to reduce involuntary muscle contractions, while diazepam offers additional muscle relaxation and anxiolytic effects. Administered rectally or vaginally, this dual-agent suppository delivers targeted relief directly to the pelvic region, commonly prescribed in urogynecology, physical therapy, and pain management settings. Our pharmacy compounds this formulation in custom strengths and bases tailored to provider-directed pelvic floor protocols.
Patients? Request More Information Prescribers? Request Prescribing AccessThis compounded suppository combines baclofen and diazepam — two complementary muscle relaxants — for stronger relief of tight, painful pelvic floor muscles. Together they ease the muscle spasm behind chronic pelvic pain, painful intercourse, vaginismus, and certain bladder and bowel symptoms more effectively than either alone. Delivered as a suppository, the medication concentrates on the pelvic floor while limiting the drowsiness of oral dosing, making it a valuable part of pelvic-floor therapy.
Prescribers and pelvic-health specialists choose this combination for patients whose pelvic muscle tension needs a stronger approach, often alongside physical therapy. We compound each suppository to the exact strengths your prescriber specifies, made to order in our pharmacy.
This suppository contains diazepam, a controlled substance, and is a compounded medication prepared to your prescription and used strictly under a prescriber's guidance. Your prescriber will set the dose, explain use, and monitor your progress. Every batch is pharmacist-compounded, quality-verified, and shipped nationwide. Prescription required.
Frequently asked questions
What does this suppository treat?
Tight, painful pelvic floor muscles behind chronic pelvic pain, painful intercourse, vaginismus, and some bladder or bowel symptoms.
Why combine two relaxants?
Baclofen and diazepam work through complementary mechanisms, so together they can relieve pelvic muscle spasm more effectively than either alone.
Is it used with physical therapy?
Often, yes — it's commonly part of a pelvic floor therapy plan coordinated by your prescriber.
Is it closely supervised?
Yes — because it contains diazepam, a controlled substance, it's used strictly under a prescriber's guidance with monitoring.
Do I need a prescription?
Yes. These suppositories are compounded to your prescriber's order and require a valid prescription. Our pharmacists prepare and verify every batch.

