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Compounded BiEst cream is a bioidentical estrogen therapy for menopause and perimenopause, combining two estrogens your body makes: estriol and estradiol. As estrogen declines, symptoms like hot flashes, night sweats, vaginal dryness, sleep disruption, and mood changes can follow. BiEst replaces estrogen in a transdermal cream, so it is absorbed through the skin and bypasses first-pass processing in the liver, which many prescribers prefer.
The blend is typically weighted toward estriol, a gentler estrogen, with a smaller amount of the more potent estradiol, and your prescriber sets the exact ratio and strength for your symptoms and goals. It is applied to the skin daily as directed, and for women with a uterus it is used together with progesterone to protect the uterine lining. Because it is compounded, we can tailor the formula in a way commercial products cannot.
Estradiol is FDA-approved and estriol is prepared as a compounded medication, so BiEst is dispensed to your prescription and used under a prescriber who tailors your hormone plan and monitoring. It is generally well tolerated; possible effects include breast tenderness, spotting, or skin irritation at the application site. Every batch is pharmacist-compounded, quality-verified, and shipped nationwide. Prescription required.
Frequently asked questions
What is BiEst cream used for?
Relieving menopause and perimenopause symptoms like hot flashes, night sweats, vaginal dryness, sleep issues, and mood changes, as part of bioidentical hormone therapy.
What is in BiEst?
A bioidentical blend of two estrogens, estriol and estradiol, usually weighted toward estriol with a smaller amount of estradiol. Your prescriber sets the ratio and strength.
Why a cream instead of a pill?
A transdermal cream is absorbed through the skin and bypasses first-pass liver processing, which many prescribers prefer. Because it is compounded, the strength and ratio are tailored to you.
Do I need progesterone with it?
If you have a uterus, estrogen is used together with progesterone to protect the uterine lining. Your prescriber will guide this.
Are there side effects?
It is generally well tolerated. Possible effects include breast tenderness, spotting, or mild skin irritation at the application site. Use under a prescriber's guidance.
New to hormone therapy? Read our full guide: our guide to bioidentical hormone therapy for menopause.
Patients? Request More Information Prescribers? Request Prescribing Access
Compounded BiEst cream is a bioidentical estrogen therapy for menopause and perimenopause, combining two estrogens your body makes: estriol and estradiol. As estrogen declines, symptoms like hot flashes, night sweats, vaginal dryness, sleep disruption, and mood changes can follow. BiEst replaces estrogen in a transdermal cream, so it is absorbed through the skin and bypasses first-pass processing in the liver, which many prescribers prefer.
The blend is typically weighted toward estriol, a gentler estrogen, with a smaller amount of the more potent estradiol, and your prescriber sets the exact ratio and strength for your symptoms and goals. It is applied to the skin daily as directed, and for women with a uterus it is used together with progesterone to protect the uterine lining. Because it is compounded, we can tailor the formula in a way commercial products cannot.
Estradiol is FDA-approved and estriol is prepared as a compounded medication, so BiEst is dispensed to your prescription and used under a prescriber who tailors your hormone plan and monitoring. It is generally well tolerated; possible effects include breast tenderness, spotting, or skin irritation at the application site. Every batch is pharmacist-compounded, quality-verified, and shipped nationwide. Prescription required.
Frequently asked questions
What is BiEst cream used for?
Relieving menopause and perimenopause symptoms like hot flashes, night sweats, vaginal dryness, sleep issues, and mood changes, as part of bioidentical hormone therapy.
What is in BiEst?
A bioidentical blend of two estrogens, estriol and estradiol, usually weighted toward estriol with a smaller amount of estradiol. Your prescriber sets the ratio and strength.
Why a cream instead of a pill?
A transdermal cream is absorbed through the skin and bypasses first-pass liver processing, which many prescribers prefer. Because it is compounded, the strength and ratio are tailored to you.
Do I need progesterone with it?
If you have a uterus, estrogen is used together with progesterone to protect the uterine lining. Your prescriber will guide this.
Are there side effects?
It is generally well tolerated. Possible effects include breast tenderness, spotting, or mild skin irritation at the application site. Use under a prescriber's guidance.
New to hormone therapy? Read our full guide: our guide to bioidentical hormone therapy for menopause.
Patients? Request More Information Prescribers? Request Prescribing Access
