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Clindamycin / Tretinoin Cream
Compounded clindamycin / tretinoin cream is a prescription-only topical formulation used to treat acne by targeting both the bacterial and comedonal components of the condition. Clindamycin is a topical antibiotic that reduces Cutibacterium acnes (formerly P. acnes) and inflammation, while tretinoin, a vitamin A derivative, increases skin cell turnover to unclog pores and improve skin texture. This dual-action therapy is ideal for patients with moderate to severe acne who need customized strengths or alternative bases for sensitive skin. Our pharmacy compounds clindamycin / tretinoin creams based on provider-directed formulas for personalized and effective acne management.
Prescribers choose this combination for inflammatory and comedonal acne because pairing an antibiotic with a retinoid is more effective than either alone. We compound each cream to the exact strengths your prescriber specifies, in a base designed for tolerability, made to order for each patient in our pharmacy.
This is a compounded medication prepared to your prescription and used under a prescriber's guidance. Your prescriber will set the concentrations and application schedule as your skin adjusts. Every batch is pharmacist-compounded, quality-verified, and shipped nationwide. Prescription required.
Frequently asked questions
How does this cream treat acne?
Clindamycin reduces acne bacteria and inflammation while tretinoin unclogs pores and renews skin — together clearing breakouts and preventing new ones.
Why combine an antibiotic and a retinoid?
They work on different causes of acne, so the pairing is more effective than either ingredient used alone.
Is it irritating?
We compound it in a base designed for tolerability, and your prescriber sets the strength and frequency so your skin can adjust.
Why choose a compounded cream?
Compounding lets your prescriber tailor both ingredients to your skin, prepared fresh for each prescription.
Do I need a prescription?
Yes. This cream is compounded to your prescriber's order and requires a valid prescription. Our pharmacists prepare and verify every batch.
Patients? Request More Information Prescribers? Request Prescribing Access
Compounded clindamycin / tretinoin cream is a prescription-only topical formulation used to treat acne by targeting both the bacterial and comedonal components of the condition. Clindamycin is a topical antibiotic that reduces Cutibacterium acnes (formerly P. acnes) and inflammation, while tretinoin, a vitamin A derivative, increases skin cell turnover to unclog pores and improve skin texture. This dual-action therapy is ideal for patients with moderate to severe acne who need customized strengths or alternative bases for sensitive skin. Our pharmacy compounds clindamycin / tretinoin creams based on provider-directed formulas for personalized and effective acne management.
Prescribers choose this combination for inflammatory and comedonal acne because pairing an antibiotic with a retinoid is more effective than either alone. We compound each cream to the exact strengths your prescriber specifies, in a base designed for tolerability, made to order for each patient in our pharmacy.
This is a compounded medication prepared to your prescription and used under a prescriber's guidance. Your prescriber will set the concentrations and application schedule as your skin adjusts. Every batch is pharmacist-compounded, quality-verified, and shipped nationwide. Prescription required.
Frequently asked questions
How does this cream treat acne?
Clindamycin reduces acne bacteria and inflammation while tretinoin unclogs pores and renews skin — together clearing breakouts and preventing new ones.
Why combine an antibiotic and a retinoid?
They work on different causes of acne, so the pairing is more effective than either ingredient used alone.
Is it irritating?
We compound it in a base designed for tolerability, and your prescriber sets the strength and frequency so your skin can adjust.
Why choose a compounded cream?
Compounding lets your prescriber tailor both ingredients to your skin, prepared fresh for each prescription.
Do I need a prescription?
Yes. This cream is compounded to your prescriber's order and requires a valid prescription. Our pharmacists prepare and verify every batch.
Patients? Request More Information Prescribers? Request Prescribing Access

