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Caffeine / GHK-Cu / Niacinamide / Tretinoin Cream
Compounded caffeine, GHK-Cu (copper peptide), niacinamide, and tretinoin cream is a prescription-only topical formulation designed to support healthier, firmer, and more youthful-appearing skin by combining ingredients that target collagen production, skin renewal, hydration, and antioxidant defense. Caffeine provides antioxidant activity while helping reduce the appearance of puffiness and improving microcirculation within the skin. GHK-Cu is a naturally occurring copper peptide studied for its ability to support collagen synthesis, extracellular matrix remodeling, wound healing, and overall skin rejuvenation. Niacinamide strengthens the skin barrier, improves hydration, minimizes redness, and promotes a more even complexion. Tretinoin accelerates epidermal turnover, stimulates collagen production, and improves the appearance of fine lines, wrinkles, uneven pigmentation, and photodamaged skin. By combining these complementary ingredients into one customized cream, prescribers can provide comprehensive anti-aging and skin rejuvenation therapy tailored to individual patient needs. Our pharmacy compounds caffeine, GHK-Cu, niacinamide, and tretinoin creams in customized strengths and elegant topical vehicles to meet dermatologist- and prescriber-directed treatment plans.
Prescribers choose this multi-ingredient cream to consolidate a full anti-aging regimen into a single tailored product. We compound each cream to the exact strengths your prescriber specifies, in a base designed to keep the retinoid well tolerated, made to order for each patient in our pharmacy.
This is a compounded medication prepared to your prescription and used under a prescriber's guidance. Your prescriber will set the concentrations and application schedule as your skin adjusts. Every batch is pharmacist-compounded, quality-verified, and shipped nationwide. Prescription required.
Frequently asked questions
What does this cream do?
It targets fine lines, firmness, tone, and brightness at once — tretinoin for turnover, GHK-Cu for repair, niacinamide for barrier and tone, caffeine for brightening and puffiness.
Why combine four ingredients?
Each addresses a different sign of aging, so one formula can replace several products and keep your routine simple.
Is it well tolerated?
We compound it in a base designed for tolerability, and your prescriber sets the strength and frequency so your skin can adjust.
Why choose a compounded cream?
Compounding lets your prescriber tailor each ingredient to your skin and goals, prepared fresh for each prescription.
Do I need a prescription?
Yes. This cream is compounded to your prescriber's order and requires a valid prescription. Our pharmacists prepare and verify every batch.
Patients? Request More Information Prescribers? Request Prescribing Access
Compounded caffeine, GHK-Cu (copper peptide), niacinamide, and tretinoin cream is a prescription-only topical formulation designed to support healthier, firmer, and more youthful-appearing skin by combining ingredients that target collagen production, skin renewal, hydration, and antioxidant defense. Caffeine provides antioxidant activity while helping reduce the appearance of puffiness and improving microcirculation within the skin. GHK-Cu is a naturally occurring copper peptide studied for its ability to support collagen synthesis, extracellular matrix remodeling, wound healing, and overall skin rejuvenation. Niacinamide strengthens the skin barrier, improves hydration, minimizes redness, and promotes a more even complexion. Tretinoin accelerates epidermal turnover, stimulates collagen production, and improves the appearance of fine lines, wrinkles, uneven pigmentation, and photodamaged skin. By combining these complementary ingredients into one customized cream, prescribers can provide comprehensive anti-aging and skin rejuvenation therapy tailored to individual patient needs. Our pharmacy compounds caffeine, GHK-Cu, niacinamide, and tretinoin creams in customized strengths and elegant topical vehicles to meet dermatologist- and prescriber-directed treatment plans.
Prescribers choose this multi-ingredient cream to consolidate a full anti-aging regimen into a single tailored product. We compound each cream to the exact strengths your prescriber specifies, in a base designed to keep the retinoid well tolerated, made to order for each patient in our pharmacy.
This is a compounded medication prepared to your prescription and used under a prescriber's guidance. Your prescriber will set the concentrations and application schedule as your skin adjusts. Every batch is pharmacist-compounded, quality-verified, and shipped nationwide. Prescription required.
Frequently asked questions
What does this cream do?
It targets fine lines, firmness, tone, and brightness at once — tretinoin for turnover, GHK-Cu for repair, niacinamide for barrier and tone, caffeine for brightening and puffiness.
Why combine four ingredients?
Each addresses a different sign of aging, so one formula can replace several products and keep your routine simple.
Is it well tolerated?
We compound it in a base designed for tolerability, and your prescriber sets the strength and frequency so your skin can adjust.
Why choose a compounded cream?
Compounding lets your prescriber tailor each ingredient to your skin and goals, prepared fresh for each prescription.
Do I need a prescription?
Yes. This cream is compounded to your prescriber's order and requires a valid prescription. Our pharmacists prepare and verify every batch.
Patients? Request More Information Prescribers? Request Prescribing Access

